PGT-M and PGT-A can be combined to study both monogenic disorders and aneuploidy starting from a single biopsy.

PGT-M and PGT-A can be combined to study both monogenic disorders and aneuploidy starting from a single biopsy.

Study both monogenic disorders and aneuploidy.

Next-generation sequencing (NGS) is currently the most effective technique available for the study of the genome. It has become an important tool for implementing PGT helped by the study of monogenic disorders and aneuploidy.

Study both monogenic disorders and aneuploidy.

PGT-M and PGT-A can be combined to study both monogenic disorders and aneuploidy starting from a single biopsy.

PGT-M + PGT-A

We enable researchers to test for both single-gene mutations and chromosomal abnormalities in embryos using a single biopsy.

Journey genomics

What it is

PGD-SEQ is a next-generation sequencing (NGS)-based genetic test that enables researchers to conduct preimplantation genetic testing (PGT) in embryos for both aneuploidies (PGT-A) and monogenic disorders (PGT-M).

PGT-M is designed to research monogenic disorders that are caused by variants within a single gene and are inheritable.

PGT-A is designed to study disorders due to chromosomal abnormalities such as aneuploidies and copy number variation. Chromosomal abnormalities occur spontaneously during mitosis and can be fatal, causing miscarriage.

Key benefits of the PGD-SEQ kit and software package:

In-house analysis of both PGT-M and PGT-A.

Obtain results within just 13 hours

Researching for more than 200 verified diseases.

Simplify your laboratory routine.

How it works

Next-generation sequencing (NGS) is currently the most effective technique available for the study of the genome. It has become an important tool for implementing PGT.

NGS offers comprehensive information concerning aneuploidies, genetic mutations, and unbalanced translocations in the samples.

With more comprehensive information, researchers can make more informed decisions for selection of healthy preimplantation embryos.

PGT-M and PGT-A can be combined to study both monogenic disorders and aneuploidy starting from a single biopsy.

Workflow for PGT-M + PGT-A by NGS

 

With PGD-SEQ, both PGT-M and PGT-A can be combined to study both monogenic disorders and aneuploidy starting from a single biopsy. In addition, multiple samples can be processed together in such a way that the per‑sample sequencing time and cost are minimized.

PGT-M and PGT-A can be combined to study both monogenic disorders and aneuploidy starting from a single biopsy.

PGT-M + PGT-A analysis can be carried out in as little as 24 hours.

Our PGT-M by NGS panels

 

To create our sequencing panels, DNA samples from both parents as well as additional family members are requested for testing.

PGT-M allows simultaneous detection of different point mutations and surrounding SNPs, to identify potential allele drop-out phenomenon, accurately calling each research embryo as affected, carrier, or unaffected.

OUR PGT-M TESTS

Panels Available & Customization

 

We currently offer more than 300 verified panels. We can also customize panels for you to study different monogenic disorders according to your research needs.

Development for human genetic testing

Parque Científico y Empresarial de la UMH
Edificio Quorum III
03202 Elche – Alicante
Spain

Phone: +34 966 261 268
Information: info@journeygenomics.com
Orders: orders@journeygenomics.com