PGT-M and PGT-A can be combined to study both monogenic disorders and aneuploidy starting from a single biopsy.
PGT-M and PGT-A can be combined to study both monogenic disorders and aneuploidy starting from a single biopsy.
Study both monogenic disorders and aneuploidy.
Next-generation sequencing (NGS) is currently the most effective technique available for the study of the genome. It has become an important tool for implementing PGT helped by the study of monogenic disorders and aneuploidy.
Study both monogenic disorders and aneuploidy.
PGT-M + PGT-A
We enable researchers to test for both single-gene mutations and chromosomal abnormalities in embryos using a single biopsy.
Journey genomics
What it is
PGD-SEQ is a next-generation sequencing (NGS)-based genetic test that enables researchers to conduct preimplantation genetic testing (PGT) in embryos for both aneuploidies (PGT-A) and monogenic disorders (PGT-M).
PGT-M is designed to research monogenic disorders that are caused by variants within a single gene and are inheritable.
PGT-A is designed to study disorders due to chromosomal abnormalities such as aneuploidies and copy number variation. Chromosomal abnormalities occur spontaneously during mitosis and can be fatal, causing miscarriage.
Key benefits of the PGD-SEQ kit and software package:
How it works
Next-generation sequencing (NGS) is currently the most effective technique available for the study of the genome. It has become an important tool for implementing PGT.
NGS offers comprehensive information concerning aneuploidies, genetic mutations, and unbalanced translocations in the samples.
With more comprehensive information, researchers can make more informed decisions for selection of healthy preimplantation embryos.
Workflow for PGT-M + PGT-A by NGS
With PGD-SEQ, both PGT-M and PGT-A can be combined to study both monogenic disorders and aneuploidy starting from a single biopsy. In addition, multiple samples can be processed together in such a way that the per‑sample sequencing time and cost are minimized.
Our PGT-M by NGS panels
To create our sequencing panels, DNA samples from both parents as well as additional family members are requested for testing.
PGT-M allows simultaneous detection of different point mutations and surrounding SNPs, to identify potential allele drop-out phenomenon, accurately calling each research embryo as affected, carrier, or unaffected.
OUR PGT-M TESTS
Panels Available & Customization
We currently offer more than 300 verified panels. We can also customize panels for you to study different monogenic disorders according to your research needs.
How to read the information:
SKU / Gene / Disease
Direct testing
Manual and Protocols
You can download the portocols and manuals clicking on the buttons bellow.
Edificio Quorum III
03202 Elche – Alicante
Spain
Information: info@journeygenomics.com
Orders: orders@journeygenomics.com